Conjoined twins, are monozygotic twins, whose bodies are joined together at birth. This occurs where the single zygote of identical twins fails to separate completely, and the zygote starts to split after day 13 following fertilization. This condition occurs in about 1 in 50,000 human pregnancies. Most conjoined twins are now evaluated for surgery to attempt to separate them into separate functional bodies. The degree of difficulty rises if a vital organ or structure is shared between twins, such as brain, heart or liver.
A chimera is an ordinary person or animal except that some of his or her parts actually came from his or her twin. A chimera may arise either from identical twin fetuses,or from dizygotic fetuses, which can be identified by chromosomal comparisons from various parts of the body. The number of cells derived from each fetus can vary from one part of the body to another, and often leads to characteristic mosaicism skin colouration in human chimeras. A chimera may be a hermaphrodite, composed of cells from a male twin and a female twin.
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